The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine Immunogens

The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine Immunogens

The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a grave threat to global public health and imposes a severe burden on the entire human society. Like other coronaviruses, the SARS-CoV-2 genome encodes spike (S)...

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Bibliographic Details
Main Authors: Liangwei Duan, Qianqian Zheng, Hongxia Zhang, Yuna Niu, Yunwei Lou, Hui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
spike glycoprotein
receptor-binding domain
synthesis
structure
membrane fusion
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.576622/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.576622/full

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