Reconciling the Biological and Transcriptional Variability of Hepatoblastoma with Its Mutational Uniformity
Hepatoblastoma (HB), the most common childhood liver cancer, is associated with seven distinct histologic subtypes and variable degrees of clinical aggressiveness and presentation. Yet it is among the least genomically altered tumors known, with about half of HBs showing mutation and/or dysregulatio...
Main Author: | Edward V. Prochownik |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/9/1996 |
Similar Items
-
Polymorphism in the Promoter Region of NFE2L2 Gene Is a Genetic Marker of Susceptibility to Cirrhosis Associated with Alcohol Abuse
by: Kemper Nunes dos Santos, et al.
Published: (2019-07-01) -
Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2
by: Anusha Chaparala, et al.
Published: (2020-06-01) -
Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis
by: Simone Marquard, et al.
Published: (2020-10-01) -
Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines
by: William F. Mueller, et al.
Published: (2020-05-01) -
EHMT2 promotes the pathogenesis of hepatocellular carcinoma by epigenetically silencing APC expression
by: Yuan Guo, et al.
Published: (2021-08-01)