Reconciling the Biological and Transcriptional Variability of Hepatoblastoma with Its Mutational Uniformity

Hepatoblastoma (HB), the most common childhood liver cancer, is associated with seven distinct histologic subtypes and variable degrees of clinical aggressiveness and presentation. Yet it is among the least genomically altered tumors known, with about half of HBs showing mutation and/or dysregulatio...

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Bibliographic Details
Main Author: Edward V. Prochownik
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/9/1996