Mycoplasma pneumoniae CARDS toxin is internalized via clathrin-mediated endocytosis.

Bacterial toxins possess specific mechanisms of binding and uptake by mammalian cells. Mycoplasma pneumoniae CARDS (Community Acquired Respiratory Distress Syndrome) toxin is a 68 kDa protein, which demonstrates high binding affinity to human surfactant protein-A and exhibits specific biological act...

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Bibliographic Details
Main Authors: Manickam Krishnan, T R Kannan, Joel B Baseman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3647021?pdf=render