Rapid Bioassay-Guided Isolation of Antibacterial Clerodane Type Diterpenoid from Dodonaea viscosa (L.) Jaeq.

Rapid Bioassay-Guided Isolation of Antibacterial Clerodane Type Diterpenoid from Dodonaea viscosa (L.) Jaeq.

Plant extracts are complex matrices and, although crude extracts are widely in use, purified compounds are pivotal in drug discovery. This study describes the application of automated preparative-HPLC combined with a rapid off-line bacterial bioassay, using reduction of a tetrazolium salt as an indi...

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Bibliographic Details
Main Authors: Muhammad Khurram, Linda A. Lawton, Christine Edwards, Marcello Iriti, Abdul Hameed, Murad A. Khan, Farman A. Khan, Shafiq ur Rahman
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Molecular Sciences
Subjects:
Dodonaea viscosa
preparative HPLC
XTT assay
clerodane diterpenoid
Online Access:http://www.mdpi.com/1422-0067/16/9/20290

Internet

http://www.mdpi.com/1422-0067/16/9/20290

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