Dihydromyricetin attenuates palmitic acid-induced oxidative stress by promoting autophagy via SIRT3-ATG4B signaling in hepatocytes

Dihydromyricetin attenuates palmitic acid-induced oxidative stress by promoting autophagy via SIRT3-ATG4B signaling in hepatocytes

Abstract Background Oxidative stress in hepatocytes was important pathogenesis of nonalcoholic steatohepatitis (NASH). Autophagy was a cellular process that can remove damaged organelles under oxidative stress, and thus presented a potential therapeutic target against NASH. This work aimed to invest...

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Bibliographic Details
Main Authors: Li Huang, Xianglong Zeng, Bo Li, Cong Wang, Min Zhou, Hedong Lang, Long Yi, Mantian Mi
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Nutrition & Metabolism
Subjects:
Dihydromyricetin
NASH
Oxidative stress
Autophagy
ATG4B
Mitochondria
Online Access:https://doi.org/10.1186/s12986-021-00612-w

Internet

https://doi.org/10.1186/s12986-021-00612-w

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