Toll-like receptors expressed by synovial fibroblasts perpetuate Th1 and th17 cell responses in rheumatoid arthritis.
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial fibroblast hyperplasia and bone and cartilage erosion. Synovial fibroblast- and T cell-mediated inflammation plays crucial roles in the pathogenesis of RA. However how this inflammation is initiated, propagated, an...
Main Authors: | Fanlei Hu, Yingni Li, Li Zheng, Lianjie Shi, Hongjiang Liu, Xuewu Zhang, Huaqun Zhu, Sumei Tang, Lei Zhu, Liling Xu, Yuqin Yang, Zhanguo Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4061069?pdf=render |
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