Toll-like receptors expressed by synovial fibroblasts perpetuate Th1 and th17 cell responses in rheumatoid arthritis.

Toll-like receptors expressed by synovial fibroblasts perpetuate Th1 and th17 cell responses in rheumatoid arthritis.

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial fibroblast hyperplasia and bone and cartilage erosion. Synovial fibroblast- and T cell-mediated inflammation plays crucial roles in the pathogenesis of RA. However how this inflammation is initiated, propagated, an...

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Bibliographic Details
Main Authors: Fanlei Hu, Yingni Li, Li Zheng, Lianjie Shi, Hongjiang Liu, Xuewu Zhang, Huaqun Zhu, Sumei Tang, Lei Zhu, Liling Xu, Yuqin Yang, Zhanguo Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4061069?pdf=render

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http://europepmc.org/articles/PMC4061069?pdf=render

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