Impact of the uremic milieu on the osteogenic potential of mesenchymal stem cells.

Human mesenchymal stem cells (hMSCs), the precursors of osteoblasts during osteogenesis, play a role in the balance of bone formation and resorption, but their functioning in uremia has not been well defined. To study the effects of the uremic milieu on osteogenic properties, we applied an in vitro...

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Bibliographic Details
Main Authors: Diana Lanza, Alessandra F Perna, Adriana Oliva, Raymond Vanholder, Anneleen Pletinck, Salvatore Guastafierro, Annarita Di Nunzio, Carmela Vigorito, Giovambattista Capasso, Vera Jankowski, Joachim Jankowski, Diego Ingrosso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4312090?pdf=render