Determining seropositivity-A review of approaches to define population seroprevalence when using multiplex bead assays to assess burden of tropical diseases.

<h4>Background</h4>Serological surveys with multiplex bead assays can be used to assess seroprevalence to multiple pathogens simultaneously. However, multiple methods have been used to generate cut-off values for seropositivity and these may lead to inconsistent interpretation of results...

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Bibliographic Details
Main Authors: YuYen Chan, Kimberly Fornace, Lindsey Wu, Benjamin F Arnold, Jeffrey W Priest, Diana L Martin, Michelle A Chang, Jackie Cook, Gillian Stresman, Chris Drakeley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009457