Mice deficient in cryptochrome 1 (Cry1-/-) exhibit resistance to obesity induced by a high fat diet

Mice deficient in cryptochrome 1 (Cry1-/-) exhibit resistance to obesity induced by a high fat diet

Disruption of circadian clock enhances the risk of metabolic syndrome, obesity, and type 2 diabetes. Circadian clocks rely on a highly regulated network of transcriptional and translational loops that drive clock-controlled gene expression. Among these transcribed clock genes are cryptochrome (CRY)...

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Bibliographic Details
Main Authors: Guy eGriebel, Christine eRavinet-Trillou, Sandra eBeeské, Patrick eAvenet, Philippe ePichat
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Endocrinology
Subjects:
Cryptochromes
Mice
Obesity
Triglycerides
knockout mice
diet-induced obesity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00049/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00049/full

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