Human islets contain four distinct subtypes of β cells

Human islets contain four distinct subtypes of β cells

Dysfunction or loss of insulin-secreting β cells in the pancreas is a hallmark of diabetes. Here, Dorrell et al.identify four subpopulations of β cells in humans, which differ in gene expression and insulin secretion kinetics, and the abundance of which is altered in patients with type 2 diabetes.

Bibliographic Details
Main Authors: Craig Dorrell, Jonathan Schug, Pamela S. Canaday, Holger A. Russ, Branden D. Tarlow, Maria T. Grompe, Tamara Horton, Matthias Hebrok, Philip R. Streeter, Klaus H. Kaestner, Markus Grompe
Format: Article
Language:English
Published: Nature Publishing Group 2016-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11756

Internet

https://doi.org/10.1038/ncomms11756

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