Binding Site Identification and Flexible Docking of Single Stranded RNA to Proteins Using a Fragment-Based Approach.

Protein-RNA docking is hampered by the high flexibility of RNA, and particularly single-stranded RNA (ssRNA). Yet, ssRNA regions typically carry the specificity of protein recognition. The lack of methodology for modeling such regions limits the accuracy of current protein-RNA docking methods. We de...

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Bibliographic Details
Main Authors: Isaure Chauvot de Beauchene, Sjoerd J de Vries, Martin Zacharias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4729675?pdf=render