Síntese e avaliação preliminar da atividade antinociceptiva de novas isoxazolil-aril-hidrazonas

Síntese e avaliação preliminar da atividade antinociceptiva de novas isoxazolil-aril-hidrazonas

New 2-isoxazoline aldehydes were synthesized, in good yields, from cycloadduct of the 1,3-dipolar cycloaddition reaction between endocyclic enecarbamate and carboethoxyformonitrile oxide (CEFNO). Condensation of these 2-isoxazoline aldehydes with several phenyl-hydrazines produced new isoxazolyl-ary...

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Bibliographic Details
Main Authors: Sílvio Leandro Gonçalves Bomfim Reis, Valderes Moraes de Almeida, Gleybson Correia de Almeida, Karinna Moura Boaviagem, Charles Christophe Du Barriere Mendes, Antônio Rodolfo de Faria, Alexandre José da Silva Góes, Laudelina Rodrigues Magalhães, Teresinha Gonçalves da Silva
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2011-01-01
Series:Química Nova
Subjects:
2-isoxazoline aldehydes
hydrazones
antinociceptive activity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000100015&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000100015&lng=en&tlng=en

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