Luteolin inhibits behavioral sensitization by blocking methamphetamine-induced MAPK pathway activation in the caudate putamen in mice.

GOAL: To investigate the effect of luteolin on methamphetamine (MA)-induced behavioral sensitization and mitogen-activated protein kinase (MAPK) signal transduction pathway activation in mice. METHODS: Mice received a single dose of MA to induce hyperactivity or repeated intermittent intraperitoneal...

Full description

Bibliographic Details
Main Authors: Tinglin Yan, Lu Li, Baiyu Sun, Fei Liu, Peng Yang, Teng Chen, Tao Li, Xinshe Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4047057?pdf=render