Proteomic Analysis of Morphologically Changed Tissues after Prolonged Dexamethasone Treatment

Proteomic Analysis of Morphologically Changed Tissues after Prolonged Dexamethasone Treatment

Prolonged dexamethasone (Dex) administration leads to serious adverse and decrease brain and heart size, muscular atrophy, hemorrhagic liver, and presence of kidney cysts. Herein, we used an untargeted proteomic approach using liquid chromatography-tandem mass spectrometry (LC-MS/MS) for simultaneou...

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Bibliographic Details
Main Authors: Abeer K. Malkawi, Afshan Masood, Zakia Shinwari, Minnie Jacob, Hicham Benabdelkamel, Goran Matic, Falah Almuhanna, Majed Dasouki, Ayodele A. Alaiya, Anas M. Abdel Rahman
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
dexamethasone
label-free proteomics
LC-MS/M
rat tissues
glucocorticoid side effects
proteomic expression
network pathway
Online Access:https://www.mdpi.com/1422-0067/20/13/3122

Internet

https://www.mdpi.com/1422-0067/20/13/3122

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