Analysis of clinical presentation, hematological factors, self-reported bed net usage, and malaria burden in sickle cell disease patients

Background: Sickle cell anemia (SCA) is a severe monogenic disorder, caused by single nucleotide mutations in the hemoglobin (Hb) gene, that is prevalent in malaria endemic regions of the world. Sickle cell trait (SCT) individuals carry only one of the mutated alleles and were shown to be protected...

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Bibliographic Details
Main Authors: Keri Oxendine Harp, Felix Botchway, Yvonne Dei-Adomakoh, Michael D. Wilson, Mohamed Mubasher, Andrew A. Adjei, Winston E. Thompson, Jonathan K. Stiles, Adel Driss
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537021003254