Mutations in Splicing Factor Genes in Myeloid Malignancies: Significance and Impact on Clinical Features
Components of the pre-messenger RNA splicing machinery are frequently mutated in myeloid malignancies. Mutations in <i>LUC7L2, PRPF8,</i> <i>SF3B1</i>, <i>SRSF2</i>, <i>U2AF1</i>, and <i>ZRSR2</i> genes occur at various frequencies ranging...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-11-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/12/1844 |