RGS12 Is a Novel Critical NF-κB Activator in Inflammatory Arthritis

Summary: Rheumatoid arthritis (RA) is the most common inflammatory disease, which currently lacks effective treatment. Here, we discovered that the Regulator of G Protein Signaling 12 (RGS12) plays a key role in regulating inflammation. Transcriptional and protein analysis revealed that RGS12 was up...

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Bibliographic Details
Main Authors: Gongsheng Yuan, Shuting Yang, Andrew Ng, Chuanyun Fu, Merry Jo Oursler, Lianping Xing, Shuying Yang
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220303576