Enhanced pre-synaptic glutamate release in deep-dorsal horn contributes to calcium channel alpha-2-delta-1 protein-mediated spinal sensitization and behavioral hypersensitivity

<p>Abstract</p> <p>Nerve injury-induced expression of the spinal calcium channel alpha-2-delta-1 subunit (Ca<sub>v</sub>α<sub>2</sub>δ<sub>1</sub>) has been shown to mediate behavioral hypersensitivity through a yet identified mechanism. We exami...

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Bibliographic Details
Main Authors: Dickenson Anthony H, Feng Guoping, Kim Doo-Sik, Matthews Elizabeth A, Deng Ping, Nguyen David, Xu Zao C, Luo Z David
Format: Article
Language:English
Published: SAGE Publishing 2009-02-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/5/1/6