Role of Aldosterone and Mineralocorticoid Receptor in Cardiovascular Aging

Role of Aldosterone and Mineralocorticoid Receptor in Cardiovascular Aging

The mineralocorticoid receptor (MR) was originally identified as a regulator of blood pressure, able to modulate renal sodium handling in response to its principal ligand aldosterone. MR is expressed in several extra-renal tissues, including the heart, vasculature, and adipose tissue. More recent st...

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Bibliographic Details
Main Authors: Stefania Gorini, Seung Kyum Kim, Marco Infante, Caterina Mammi, Sandro La Vignera, Andrea Fabbri, Iris Z. Jaffe, Massimiliano Caprio
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Endocrinology
Subjects:
endothelial dysfunction
mineralocorticoid receptor
vascular stiffness
RAAS
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00584/full

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https://www.frontiersin.org/article/10.3389/fendo.2019.00584/full

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