Cancer Risks Linked to the Bad Luck Hypothesis and Epigenomic Mutational Signatures

Exposure to pathogen infection, and occupational and environmental agents, contributes to induction of most types of cancer through different mechanisms. Cancer is defined and characterized by accumulation of mutations and epimutations that lead to changes in the cellular genome and epigenome. Accor...

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Bibliographic Details
Main Author: José E. Belizário
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Epigenomes
Subjects:
Online Access:http://www.mdpi.com/2075-4655/2/3/13