Cadmium alters the formation of benzo[a]pyrene DNA adducts in the RPTEC/TERT1 human renal proximal tubule epithelial cell line

Cadmium alters the formation of benzo[a]pyrene DNA adducts in the RPTEC/TERT1 human renal proximal tubule epithelial cell line

Previously, we demonstrated the sensitivity of RPTEC/TERT1 cells, an immortalized human renal proximal tubule epithelial cell line, to two common environmental carcinogens, cadmium (Cd) and benzo[a]pyrene (B[a]P). Here, we measured BPDE-DNA adducts using a competitive ELISA method after cells were e...

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Bibliographic Details
Main Authors: Bridget R. Simon, Mark J. Wilson, Diane A. Blake, Haini Yu, Jeffrey K. Wickliffe
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Toxicology Reports
Subjects:
Mixtures toxicology
BPDE-DNA adducts
Renal cancer
RPTEC/TERT1
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014000468

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http://www.sciencedirect.com/science/article/pii/S2214750014000468

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