Chemometric-Assisted Spectrophotometric Method for the Simultaneous Determination of Ciprofloxacin and Doxycycline Hyclate in Pharmaceutical Formulations

Two chemometrics methods—principal component regression and partial least squares—were developed for simultaneous spectrophotometric estimation of ciprofloxacin and doxycycline hyclate in pharmaceutical dosage forms without any pretreatment. The UV spectra of both drugs were recorded at concentratio...

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Bibliographic Details
Main Authors: Tadele Eticha, Getu Kahsay, Fitsum Asefa, Teklebrhan Hailu, Hailekiros Gebretsadik, Tesfamichael Gebretsadikan, Boovizhikannan Thangabalan
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2018/9538435