The heterochronic genes lin-28a and lin-28b play an essential and evolutionarily conserved role in early zebrafish development.

The Caenorhabditis elegans heterochronic gene pathway, which consists of a set of regulatory genes, plays an important regulatory role in the timing of stage-specific cell lineage development in nematodes. Research into the heterochronic gene pathway gave rise to landmark microRNA (miRNA) studies an...

Full description

Bibliographic Details
Main Authors: Yasuo Ouchi, Jyunya Yamamoto, Takashi Iwamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3916362?pdf=render