Regulation of heterochromatin assembly on unpaired chromosomes during Caenorhabditis elegans meiosis by components of a small RNA-mediated pathway.

Many organisms have a mechanism for down regulating the expression of non-synapsed chromosomes and chromosomal regions during meiosis. This phenomenon is thought to function in genome defense. During early meiosis in Caenorhabditis elegans, unpaired chromosomes (e.g., the male X chromosome) become e...

Full description

Bibliographic Details
Main Authors: Xingyu She, Xia Xu, Alexander Fedotov, William G Kelly, Eleanor M Maine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2726613?pdf=render