scDual-Seq: mapping the gene regulatory program of Salmonella infection by host and pathogen single-cell RNA-sequencing

Abstract The interaction between a pathogen and a host is a highly dynamic process in which both agents activate complex programs. Here, we introduce a single-cell RNA-sequencing method, scDual-Seq, that simultaneously captures both host and pathogen transcriptomes. We use it to study the process of...

Full description

Bibliographic Details
Main Authors: Gal Avital, Roi Avraham, Amy Fan, Tamar Hashimshony, Deborah T. Hung, Itai Yanai
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-017-1340-x