Emerging Roles of Lysyl Oxidases in the Cardiovascular System: New Concepts and Therapeutic Challenges

Emerging Roles of Lysyl Oxidases in the Cardiovascular System: New Concepts and Therapeutic Challenges

Lysyl oxidases (LOX and LOX-likes (LOXLs) isoenzymes) belong to a family of copper-dependent enzymes classically involved in the covalent cross-linking of collagen and elastin, a pivotal process that ensures extracellular matrix (ECM) stability and provides the tensile and elastic characteristics of...

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Bibliographic Details
Main Authors: José Martínez-González, Saray Varona, Laia Cañes, María Galán, Ana M Briones, Victoria Cachofeiro, Cristina Rodríguez
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Biomolecules
Subjects:
lysyl oxidases
cardiovascular diseases
atherosclerosis
aortic aneurysm
vascular calcification
vascular stiffness
myocardial fibrosis
Online Access:https://www.mdpi.com/2218-273X/9/10/610

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https://www.mdpi.com/2218-273X/9/10/610

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