YidC and SecYEG form a heterotetrameric protein translocation channel
Abstract The heterotrimeric SecYEG complex cooperates with YidC to facilitate membrane protein insertion by an unknown mechanism. Here we show that YidC contacts the interior of the SecY channel resulting in a ligand-activated and voltage-dependent complex with distinct ion channel characteristics....
Main Authors: | Ilie Sachelaru, Lukas Winter, Denis G. Knyazev, Mirjam Zimmermann, Andreas Vogt, Roland Kuttner, Nicole Ollinger, Christine Siligan, Peter Pohl, Hans-Georg Koch |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-00109-8 |
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