YidC and SecYEG form a heterotetrameric protein translocation channel

Abstract The heterotrimeric SecYEG complex cooperates with YidC to facilitate membrane protein insertion by an unknown mechanism. Here we show that YidC contacts the interior of the SecY channel resulting in a ligand-activated and voltage-dependent complex with distinct ion channel characteristics....

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Bibliographic Details
Main Authors: Ilie Sachelaru, Lukas Winter, Denis G. Knyazev, Mirjam Zimmermann, Andreas Vogt, Roland Kuttner, Nicole Ollinger, Christine Siligan, Peter Pohl, Hans-Georg Koch
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00109-8