Checkpoint molecule PD-1-assisted CD8+ T lymphocyte count in tumor microenvironment predicts overall survival of patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors

Checkpoint molecule PD-1-assisted CD8+ T lymphocyte count in tumor microenvironment predicts overall survival of patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors

Jiaxi Yao,* Wei Xi,* Yanjun Zhu, Hang Wang, Xiaoyi Hu, Jianming Guo Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China *These authors contributed equally to this work Purpose: The aim of this study was to determine whether CD8+ T lymphocyte and its checkpoint-associated mod...

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Bibliographic Details
Main Authors: Yao J, Xi W, Zhu Y, Wang H, Hu X, Guo J
Format: Article
Language:English
Published: Dove Medical Press 2018-09-01
Series:Cancer Management and Research
Subjects:
metastatic renal cell carcinoma
tyrosine kinase inhibitors
immune checkpoint
prognostic factor
Online Access:https://www.dovepress.com/checkpoint-molecule-pd-1-assisted-cd8-t-lymphocyte-count-in-tumor-micr-peer-reviewed-article-CMAR

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https://www.dovepress.com/checkpoint-molecule-pd-1-assisted-cd8-t-lymphocyte-count-in-tumor-micr-peer-reviewed-article-CMAR

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