Protocol for purification and identification of MHC class I immunopeptidome from cancer cell lines

Summary: Major histocompatibility complexes (MHC) play a critical role in immunity by presenting peptides on the cell surface for T cell recognition. Identification of these peptides can be valuable to develop vaccines or immunotherapeutic strategies for infectious diseases and cancers. Mass spectro...

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Bibliographic Details
Main Authors: Sonali V. Mohan, Keshava K. Datta, Rebekah Ziegman, Corey Smith, Harsha Gowda
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721000927