Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma.

Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma.

To gain molecular insights of HBV integration that may contribute to HCC tumorigenesis, we performed whole transcriptome sequencing and whole genome copy number profiling of hepatocellular carcinoma (HCC) samples from 50 Chinese patients. We identified a total of 33 HBV-human integration sites in 16...

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Bibliographic Details
Main Authors: Hua Dong, Lan Zhang, Ziliang Qian, Xuehua Zhu, Guanshan Zhu, Yunqin Chen, Xiaoying Xie, Qinghai Ye, Jie Zang, Zhenggang Ren, Qunsheng Ji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0123175

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https://doi.org/10.1371/journal.pone.0123175

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