Triple combination of amantadine, ribavirin, and oseltamivir is highly active and synergistic against drug resistant influenza virus strains in vitro.

The rapid emergence and subsequent spread of the novel 2009 Influenza A/H1N1 virus (2009 H1N1) has prompted the World Health Organization to declare the first pandemic of the 21st century, highlighting the threat of influenza to public health and healthcare systems. Widespread resistance to both cla...

Full description

Bibliographic Details
Main Authors: Jack T Nguyen, Justin D Hoopes, Minh H Le, Donald F Smee, Amy K Patick, Dennis J Faix, Patrick J Blair, Menno D de Jong, Mark N Prichard, Gregory T Went
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2825274?pdf=render