Activation of mGlu3 receptors stimulates the production of GDNF in striatal neurons.
Metabotropic glutamate (mGlu) receptors have been considered potential targets for the therapy of experimental parkinsonism. One hypothetical advantage associated with the use of mGlu receptor ligands is the lack of the adverse effects typically induced by ionotropic glutamate receptor antagonists,...
Main Authors: | , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-08-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2719807?pdf=render |