Downregulated expression of hepatoma-derived growth factor inhibits migration and invasion of prostate cancer cells by suppressing epithelial-mesenchymal transition and MMP2, MMP9.

Hepatoma-derived growth factor (HDGF) is commonly over-expressed and plays critical roles in the development and progression in a variety of cancers. It has previously been shown that HDGF is overregulated in prostate cancer cells compared to normal prostate cells, which is correlated with cellular...

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Bibliographic Details
Main Authors: Feilong Yang, Nengwang Yu, Hui Wang, Cong Zhang, Zhao Zhang, Yanxiang Li, Dawei Li, Lei Yan, Hainan Liu, Zhonghua Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5754131?pdf=render