Effect of pharmacokinetic/pharmacodynamic ratio on tigecycline clinical response and toxicity in critically ill patients with multidrug-resistant Gram-negative infections

Introduction: The information about the pharmacokinetics and optimal dose of tigecycline in critically ill patients with severe underlying diseases is limited and controversial. In this study, we evaluate the pharmacokinetic parameters of tigecycline in critically ill patients with multidrug-resista...

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Bibliographic Details
Main Authors: Jesus Ruiz, Paula Ramirez, Esther Villarreal, Mónica Gordon, María Ángeles Sánchez, María Martín, Álvaro Castellanos-Ortega
Format: Article
Language:English
Published: SAGE Publishing 2020-09-01
Series:SAGE Open Medicine
Online Access:https://doi.org/10.1177/2050312120958897