Novel perspectives of target-binding by the evolutionarily conserved PP4 phosphatase

Protein phosphatase 4 (PP4) is an evolutionarily conserved and essential Ser/Thr phosphatase that regulates cell division, development and DNA repair in eukaryotes. The major form of PP4, present from yeast to human, is the PP4c-R2-R3 heterotrimeric complex. The R3 subunit is responsible for substra...

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Bibliographic Details
Main Authors: Zoltan Karman, Zsuzsanna Rethi-Nagy, Edit Abraham, Lilla Fabri-Ordogh, Akos Csonka, Peter Vilmos, Janusz Debski, Michal Dadlez, David M. Glover, Zoltan Lipinszki
Format: Article
Language:English
Published: The Royal Society 2020-12-01
Series:Open Biology
Subjects:
pp4
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200343