Targeting sialic acid dependent and independent pathways of invasion in Plasmodium falciparum.

The pathology of malaria is a consequence of the parasitaemia which develops through the cyclical asexual replication of parasites in a patient's red blood cells. Multiple parasite ligand-erythrocyte receptor interactions must occur for successful Plasmodium invasion of the human red cell. Two...

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Bibliographic Details
Main Authors: Rosalynn Louise Ord, Marilis Rodriguez, Tsutomu Yamasaki, Satoru Takeo, Takafumi Tsuboi, Cheryl A Lobo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3257272?pdf=render