Targeting the Janus Kinase Family in Autoimmune Skin Diseases

Autoimmune skin diseases are characterized by significant local and systemic inflammation that is largely mediated by the Janus kinase (JAK)–signal transducer and activator of transcription (STAT) pathway. Advanced understanding of this pathway has led to the development of targeted inhibitors of Ja...

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Bibliographic Details
Main Authors: Michael D. Howell, Fiona I. Kuo, Paul A. Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02342/full