The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells
<p>Abstract</p> <p>Bortezomib is a novel anti-cancer agent which has shown promising activity in non-small lung cancer (NSCLC) patients. However, only a subset of patients respond to this treatment. We show that NSCLC cell lines are differentially sensitive to bortezomib, IC<sub...
Main Authors: | Chęcińska Agnieszka, Voortman Jens, Giaccone Giuseppe |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2007-11-01
|
Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/6/1/73 |
Similar Items
-
Severe reversible cardiac failure after bortezomib treatment combined with chemotherapy in a non-small cell lung cancer patient: a case report
by: Giaccone Giuseppe, et al.
Published: (2006-05-01) -
Inhibition of 26S proteasome by Bortezomib enhances chemo drug-mediated cell toxicity in small cell lung cancer
by: Yen, Yi-Xiang, et al.
Published: (2014) -
Prediction of outcome of non-small cell lung cancer patients treated with chemotherapy and bortezomib by time-course MALDI-TOF-MS serum peptide profiling
by: Giaccone Giuseppe, et al.
Published: (2009-09-01) -
Bortezomib Amplifies Effect on Intracellular Proteasomes by Changing Proteasome Structure
by: David S. Pitcher, et al.
Published: (2015-07-01) -
Effects of Proteasome inhibitor bortezomib on apoptosis of murine alloreactive T cells in vitro
by: WANG Xu, et al.
Published: (2019-10-01)