The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells

<p>Abstract</p> <p>Bortezomib is a novel anti-cancer agent which has shown promising activity in non-small lung cancer (NSCLC) patients. However, only a subset of patients respond to this treatment. We show that NSCLC cell lines are differentially sensitive to bortezomib, IC<sub...

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Bibliographic Details
Main Authors: Chęcińska Agnieszka, Voortman Jens, Giaccone Giuseppe
Format: Article
Language:English
Published: BMC 2007-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/6/1/73