Stimulation of Na(+)/H(+) exchanger isoform 1 promotes microglial migration.

Regulation of microglial migration is not well understood. In this study, we proposed that Na(+)/H(+) exchanger isoform 1 (NHE-1) is important in microglial migration. NHE-1 protein was co-localized with cytoskeletal protein ezrin in lamellipodia of microglia and maintained its more alkaline intrace...

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Bibliographic Details
Main Authors: Yejie Shi, Hui Yuan, Dong Kim, Vishal Chanana, Akemichi Baba, Toshio Matsuda, Pelin Cengiz, Peter Ferrazzano, Dandan Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3749130?pdf=render