Endothelial Cell-Derived SO2 Controls Endothelial Cell Inflammation, Smooth Muscle Cell Proliferation, and Collagen Synthesis to Inhibit Hypoxic Pulmonary Vascular Remodelling

Endothelial Cell-Derived SO2 Controls Endothelial Cell Inflammation, Smooth Muscle Cell Proliferation, and Collagen Synthesis to Inhibit Hypoxic Pulmonary Vascular Remodelling

Hypoxic pulmonary vascular remodelling (PVR) is the major pathological basis of aging-related chronic obstructive pulmonary disease and obstructive sleep apnea syndrome. The pulmonary artery endothelial cell (PAEC) inflammation, and pulmonary artery smooth muscle cell (PASMC) proliferation, hypertro...

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Bibliographic Details
Main Authors: Xin Liu, Shangyue Zhang, Xiuli Wang, Yuanyuan Wang, Jingyuan Song, Chufan Sun, Guozhen Chen, Guosheng Yang, Yinghong Tao, Yongyan Hu, Dingfang Bu, Yaqian Huang, Junbao Du, Hongfang Jin
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/5577634

Internet

http://dx.doi.org/10.1155/2021/5577634

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