Hydrophobic collapse of trigger factor monomer in solution.

Trigger factor (TF) is a chaperone, found in bacterial cells and chloroplasts, that interacts with nascent polypeptide chains to suppress aggregation. While its crystal structure has been resolved, the solution structure and dynamics are largely unknown. We performed multiple molecular dynamics simu...

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Bibliographic Details
Main Authors: Kushagra Singhal, Jocelyne Vreede, Alireza Mashaghi, Sander J Tans, Peter G Bolhuis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23565160/?tool=EBI