Zinc as a modulator of transglutaminase activity – Laboratory and pathophysiological aspects
For a whole century, citrate has been used as an in vitro anticoagulant via chelation of calcium. Later, also EDTA was introduced as an anticoagulant. An often overlooked fact is that zinc is bound to citrate and EDTA with affinities much greater than that for calcium, imposing problems in biomedica...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Journal of Translational Autoimmunity |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589909021000307 |