A robust semi-supervised NMF model for single cell RNA-seq data

Background Single-cell RNA-sequencing (scRNA-seq) technology is a powerful tool to study organism from a single cell perspective and explore the heterogeneity between cells. Clustering is a fundamental step in scRNA-seq data analysis and it is the key to understand cell function and constitutes the...

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Bibliographic Details
Main Authors: Peng Wu, Mo An, Hai-Ren Zou, Cai-Ying Zhong, Wei Wang, Chang-Peng Wu
Format: Article
Language:English
Published: PeerJ Inc. 2020-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10091.pdf