Tomoregulin-1 prevents cardiac hypertrophy after pressure overload in mice by inhibiting TAK1-JNK pathways

Cardiac hypertrophy is associated with many forms of heart disease, and identifying important modifier genes involved in the pathogenesis of cardiac hypertrophy could lead to the development of new therapeutic strategies. Tomoregulin-1 is a growth factor that is primarily involved in embryonic devel...

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Bibliographic Details
Main Authors: Dan Bao, Dan Lu, Ning Liu, Wei Dong, Ying-Dong Lu, Chuan Qin, Lian-Feng Zhang
Format: Article
Language:English
Published: The Company of Biologists 2015-08-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/8/8/795