IgE Antibodies: From Structure to Function and Clinical Translation

IgE Antibodies: From Structure to Function and Clinical Translation

Immunoglobulin E (IgE) antibodies are well known for their role in mediating allergic reactions, and their powerful effector functions activated through binding to Fc receptors FcεRI and FcεRII/CD23. Structural studies of IgE-Fc alone, and when bound to these receptors, surprisingl...

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Bibliographic Details
Main Authors: Brian J. Sutton, Anna M. Davies, Heather J. Bax, Sophia N. Karagiannis
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Antibodies
Subjects:
Immunoglobulin E
FcεRI
CD23
allostery
cancer immunotherapy
AllergoOncology
IgE effector functions
monocytes
macrophages
ADCC
Online Access:https://www.mdpi.com/2073-4468/8/1/19

Internet

https://www.mdpi.com/2073-4468/8/1/19

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