Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection

Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection

Oncoproteins from high-risk human papillomaviruses (HPV) downregulate the transcription of the class I major histocompatibility complex (MHC-I) antigen presentation apparatus in tissue culture model systems. This could allow infected or transformed cells to evade the adaptive immune response. Using...

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Bibliographic Details
Main Authors: Steven F. Gameiro, Ali Zhang, Farhad Ghasemi, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Viruses
Subjects:
human papillomavirus
MHC-I
major histocompatibility complex
antigen presentation
immune evasion
head &amp
neck carcinoma
cervical carcinoma
Online Access:https://www.mdpi.com/1999-4915/9/9/252

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https://www.mdpi.com/1999-4915/9/9/252

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